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Reimagine Sample Management

Ledger™ is the intelligent backbone of modern research uniting data, automation, and insight across every lab process.

End-to-End Visibility. Unmatched Control.

From inventory to fulfillment, Ledger™ delivers solutions at every step.

Ledger™ transforms the way labs manage samples, eliminating the chaos of disconnected tools, manual records, and legacy systems. Built for speed, scale, and scientific robustness, it’s the foundation of a more connected R&D ecosystem.

Ledger™ is a comprehensive platform that enables real-time collaboration and decision-making. Ledger’s API-first architecture provides the agility required for discovery science, QC, and automation environments alike.

Unified inventory, requests, and fulfillment tracking

Smart logic adapts to your workflows and instruments

Supports any sample type – small molecules, biologics, tissues etc

Integrates seamlessly with your data and automation

  • EXPLORE LEDGER:
  • Work Hub
  • Requesting
  • Fulfillment
  • Admin tools
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Workhub

Orchestrate Every Task, Seamlessly

Unified Task Control

Assign, track, and complete all work from a single interface

Customizable Views

Each user sees exactly what matters to them

Real-Time Sync

Automatic updates keep everyone aligned and informed

Data-Driven Insight

Identify bottlenecks before they affect throughput

Once requests reach the lab, efficiency and alignment are everything

Whether you’re a team of one or a global organization, Ledger™ Work Hub gives you total control over in-lab processes – tracking, assigning, and delivering work seamlessly across sites and teams.

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Requesting

Request Smarter. Deliver Faster.

Easy to use

Scientists focus on outcomes, not inventory

Request templates on the fly

Create, reuse, or adapt instantly

Industry leader in sample security

Sophisticated sample access across teams and systems.

Cascading workflows

Intelligent logic triggers the next step automatically

Ledger™ makes requesting effortless

It’s intuitive for scientists, powerful for administrators, and trusted by every lab it touches. Validation engine automates source selection – removes guesswork and manual searching.

Ledger™ provides end users with an intuitive, guided experience while giving lab operators full control over how samples are fulfilled. Scientists request results, not containers — they don’t need to understand storage hierarchies or handle inventory manually.

Ledger’s intelligent validation engine applies your business logic automatically, selecting the optimal container, validating the data, and giving users full visibility into what was chosen and why.

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Fulfillment

Fulfillment Without Friction

Automated

Full instrument and data connectivity.  2 clicks and you’re running most complex systems.

Standalone

Get the files you need for key bench top instruments, no hassle, easy to use tools to process results.

Manual

Track every aspect of in lab operations. Hand pipette with confidence and data integrity.

Ledger™ fulfillment tools sit at the center of lab operations, combining operator workflows with full traceability of all work and data.

Sample management operations span many processes and hardware systems. Ledger provides flexible fulfillment tools that support what you need today and adapt as your workflows evolve.

Built for real-world sample operations

Sample management is never a single workflow. Ledger supports a wide range of operational processes across storage, handling, movement, and fulfillment, reflecting how labs actually work.

Designed to work with diverse hardware

From manual workflows to integrated automation and instrumentation, Ledger accommodates varied hardware environments without forcing operational compromise.

Adopt only what you need

Ledger fulfillment tools are modular, allowing teams to implement the capabilities required for their current process without unnecessary complexity.

Ready for change and scale

As processes grow, shift, or become more automated, Ledger adjusts with them, preserving data continuity, operator ease, and system integrity.

Weigh

  • Native integration with commonly used laboratory balances
  • Configurable to your specific workflows, rules, and tolerances
  • Delivers up to 30 percent faster processing compared to typical balance integrations

Storage Systems

  • Unified, intuitive interface across all storage types
  • Integration with any automated storage system
  • Complete toolset for accurate and traceable manual storage management

Benchtop Devices

  • Execute protocols while keeping data aligned automatically
  • Ledger generates system-specific input files for any supported device
  • Ingest output files directly from benchtop instruments when required

Manual Processes

  • Even the pipette deserves first-class tooling
  • All sample movements and transformations are captured through an easy-to-use interface
  • Preview values and calculations before execution, then commit final work with confidence

Liquid Handling

  • Direct integration with Tecan, Hamilton, Beckman, and other liquid handling platforms
  • Single, consistent dashboard that enables cross-training and reduces reliance on individual experts
  • Capture rich automation data and leverage it for downstream analysis and AI modeling

Acoustic

  • Dynamic curve calculation with the ability to adjust curves at the run level
  • Best-in-class performance that can increase system throughput by up to fivefold
  • Echo platforms generate some of the richest fulfillment data available, and Ledger ensures it is fully captured and usable
  • Ledger Acoustic delivers millions of samples every month at production scale
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Admin Tools

Configure with Confidence

Granular role-based access control

On-the-fly template and rule creation

Immutable audit trails for every change

Ledger™’s Admin Tools make governance simple and transparent

Permissions, workflows, and business rules are fully configurable without IT overhead – enabling scientists to stay compliant while moving faster.

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Integrations – Your Lab, Unified

Ledger™ connects seamlessly to the systems you rely on – and those you’ll add next.

Ledger™ integrates without friction. From small instruments to enterprise-scale automation systems, it becomes your data and process backbone – keeping every system in sync and every sample accounted for.

Native integrations with Tecan, Hamilton, Beckman, and Echo

Supports both API-based and file exchange connections

Live visibility across stores, balances, and liquid handlers

Automated Stores

Integrated Platform

Liquid Handling

Other Lab Devices

Software Integrations

Ask About Compatibility

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Ready to see Ledger in action? Get in touch today to schedule a personalized demo and discover how we can streamline your lab.

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Simplicis Consulting, LLC

8520 Allison Pointe Blvd, Suite 220
Indianapolis, IN 46250 USA

“Simplicis gives us added value over other competitors’ software at a more attractive price point.”

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“The turnaround time and consultative feedback from Simplicis have been excellent, they clearly understand compound management.”

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“Simplicis offered improvement suggestions during the requirements phase and adapted to our feedback seamlessly.”

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