The data backbone of sample management since 2007
A single LIMS where samples, data, hardware and discovery move together.

Innovation delivered
We work with global pharma, biotechs, and research organizations.
We apply deep domain expertise and listen closely to deliver a flexible platform built for real scientific work. Integrating data, automation and providing in lab quality of life solutions is the core of what we do.
Built by a team that understands samples, data, automation, & scale
Ledger was built by people who understand the realities of scientific discovery, delivering a platform that keeps samples, data, and automation aligned as labs scale and evolve.
Our engineers have all spent time in the lab – understanding the daily challenges is the best way to deliver value. Our data architecture looks to the future and is built to support large scale AI initiatives.
Founders in the spotlight

Bryan Wrench
Co-Founder & CTO
Modal Title

Heather Colvan
Co-Founder & COO

About the Bird
The cardinal is the state bird of Indiana, where Simplicis was founded. We’re proud of our Midwest roots where dedication and hard work are central to everything we do.
Cardinals do not migrate, they adapt. They remain present through changing conditions, visible and reliable year-round. This quality resonates with Simplicis – our clients live in an evolving world, we’re an ever-present partner in that scientific evolution.
The bird is not just a mascot. It is a symbol of steadiness, adaptability, and focus.
Book a demo today
Ready to see Ledger in action? Get in touch today to schedule a personalized demo and discover how we can streamline your lab.